Cargando…

Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011

BACKGROUND/AIMS: In Korea, hepatitis C is included as an infectious disease in a sentinel surveillance system. Recently, a large variation in hepatitis C incidence between different regions in Korea has been noticed. The current study verified the nationwide distribution of hepatitis C infection for...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Geun-Yong, Lee, Hyungmin, Gwack, Jin, Lee, Sang-Won, Ki, Moran, Youn, Seung-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113042/
https://www.ncbi.nlm.nih.gov/pubmed/25071909
http://dx.doi.org/10.5009/gnl.2014.8.4.428
_version_ 1782328237590839296
author Kwon, Geun-Yong
Lee, Hyungmin
Gwack, Jin
Lee, Sang-Won
Ki, Moran
Youn, Seung-Ki
author_facet Kwon, Geun-Yong
Lee, Hyungmin
Gwack, Jin
Lee, Sang-Won
Ki, Moran
Youn, Seung-Ki
author_sort Kwon, Geun-Yong
collection PubMed
description BACKGROUND/AIMS: In Korea, hepatitis C is included as an infectious disease in a sentinel surveillance system. Recently, a large variation in hepatitis C incidence between different regions in Korea has been noticed. The current study verified the nationwide distribution of hepatitis C infection for effective prevention and management. METHODS: We counted the number of hepatitis C patients who visited a hospital per county using the National Health Insurance database from 2007 to 2011. The age-adjusted prevalence ratio was used, and the age adjustment method was used as an indirect standardization method. Disease mapping and spatial analysis were conducted using a geographic information system. RESULTS: The annual prevalence of diagnosed hepatitis C was approximately 0.12% to 0.13% in Korea. The age-adjusted prevalence ratios in Busan, Jeonnam, and Gyeongnam were high (1.75, 1.4, and 1.3, respectively). The three regions in the southern coastal area of the Korean Peninsula were identified as a high-prevalence cluster (Moran’s index, 0.3636). CONCLUSIONS: The present study showed that hepatitis C infection has very large regional variation, and there are several high-risk areas. Preventive measures focusing on these areas should be applied to block the transmission of hepatitis C and reduce the disease burden.
format Online
Article
Text
id pubmed-4113042
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Gut and Liver
record_format MEDLINE/PubMed
spelling pubmed-41130422014-07-28 Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011 Kwon, Geun-Yong Lee, Hyungmin Gwack, Jin Lee, Sang-Won Ki, Moran Youn, Seung-Ki Gut Liver Original Article BACKGROUND/AIMS: In Korea, hepatitis C is included as an infectious disease in a sentinel surveillance system. Recently, a large variation in hepatitis C incidence between different regions in Korea has been noticed. The current study verified the nationwide distribution of hepatitis C infection for effective prevention and management. METHODS: We counted the number of hepatitis C patients who visited a hospital per county using the National Health Insurance database from 2007 to 2011. The age-adjusted prevalence ratio was used, and the age adjustment method was used as an indirect standardization method. Disease mapping and spatial analysis were conducted using a geographic information system. RESULTS: The annual prevalence of diagnosed hepatitis C was approximately 0.12% to 0.13% in Korea. The age-adjusted prevalence ratios in Busan, Jeonnam, and Gyeongnam were high (1.75, 1.4, and 1.3, respectively). The three regions in the southern coastal area of the Korean Peninsula were identified as a high-prevalence cluster (Moran’s index, 0.3636). CONCLUSIONS: The present study showed that hepatitis C infection has very large regional variation, and there are several high-risk areas. Preventive measures focusing on these areas should be applied to block the transmission of hepatitis C and reduce the disease burden. Gut and Liver 2014-07 2014-04-23 /pmc/articles/PMC4113042/ /pubmed/25071909 http://dx.doi.org/10.5009/gnl.2014.8.4.428 Text en Copyright © 2014 by The Korean Society of Gastroenterology, the Korean Society of Gastrointestinal Endoscopy, the Korean Society of Neurogastroenterology and Motility, Korean College of Helicobacter and Upper Gastrointestinal Research, Korean Association for the Study of Intestinal Diseases, the Korean Association for the Study of the Liver, Korean Pancreatobiliary Association, and Korean Society of Gastrointestinal Cancer. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kwon, Geun-Yong
Lee, Hyungmin
Gwack, Jin
Lee, Sang-Won
Ki, Moran
Youn, Seung-Ki
Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title_full Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title_fullStr Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title_full_unstemmed Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title_short Regional Distribution of Hepatitis C Virus Infection in the Republic of Korea, 2007–2011
title_sort regional distribution of hepatitis c virus infection in the republic of korea, 2007–2011
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113042/
https://www.ncbi.nlm.nih.gov/pubmed/25071909
http://dx.doi.org/10.5009/gnl.2014.8.4.428
work_keys_str_mv AT kwongeunyong regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011
AT leehyungmin regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011
AT gwackjin regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011
AT leesangwon regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011
AT kimoran regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011
AT younseungki regionaldistributionofhepatitiscvirusinfectionintherepublicofkorea20072011