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Hyaluronan and Hyaluronan-Binding Proteins Accumulate in Both Human Type 1 Diabetic Islets and Lymphoid Tissues and Associate With Inflammatory Cells in Insulitis
Hyaluronan (HA) is an extracellular matrix glycosaminoglycan that is present in pancreatic islets, but little is known about its involvement in the development of human type 1 diabetes (T1D). We have evaluated whether pancreatic islets and lymphoid tissues of T1D and nondiabetic organ donors differ...
Autores principales: | Bogdani, Marika, Johnson, Pamela Y., Potter-Perigo, Susan, Nagy, Nadine, Day, Anthony J., Bollyky, Paul L., Wight, Thomas N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113060/ https://www.ncbi.nlm.nih.gov/pubmed/24677718 http://dx.doi.org/10.2337/db13-1658 |
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