Chronic Reduction of Plasma Free Fatty Acid Improves Mitochondrial Function and Whole-Body Insulin Sensitivity in Obese and Type 2 Diabetic Individuals

Insulin resistance and dysregulation of free fatty acid (FFA) metabolism are core defects in type 2 diabetic (T2DM) and obese normal glucose tolerant (NGT) individuals. Impaired muscle mitochondrial function (reduced ATP synthesis) also has been described in insulin-resistant T2DM and obese subjects...

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Detalles Bibliográficos
Autores principales: Daniele, Giuseppe, Eldor, Roy, Merovci, Aurora, Clarke, Geoffrey D., Xiong, Juan, Tripathy, Devjit, Taranova, Anna, Abdul-Ghani, Muhammad, DeFronzo, Ralph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113069/
https://www.ncbi.nlm.nih.gov/pubmed/24353180
http://dx.doi.org/10.2337/db13-1130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113069/
https://www.ncbi.nlm.nih.gov/pubmed/24353180
http://dx.doi.org/10.2337/db13-1130

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