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Communication, the centrosome and the immunological synapse

Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show paralle...

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Detalles Bibliográficos
Autores principales: Stinchcombe, Jane C., Griffiths, Gillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113107/
https://www.ncbi.nlm.nih.gov/pubmed/25047617
http://dx.doi.org/10.1098/rstb.2013.0463
Descripción
Sumario:Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show parallels to centrosome (basal body) polarization seen in cilia and flagella, and the cellular communication that is now known to occur at all of these sites.