Communication, the centrosome and the immunological synapse

Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show paralle...

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Detalles Bibliográficos
Autores principales: Stinchcombe, Jane C., Griffiths, Gillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Part III: Functions of centrosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113107/
https://www.ncbi.nlm.nih.gov/pubmed/25047617
http://dx.doi.org/10.1098/rstb.2013.0463
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author Stinchcombe, Jane C.
Griffiths, Gillian M.
author_facet Stinchcombe, Jane C.
Griffiths, Gillian M.
author_sort Stinchcombe, Jane C.
collection PubMed
description Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show parallels to centrosome (basal body) polarization seen in cilia and flagella, and the cellular communication that is now known to occur at all of these sites.
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spelling pubmed-41131072014-09-05 Communication, the centrosome and the immunological synapse Stinchcombe, Jane C. Griffiths, Gillian M. Philos Trans R Soc Lond B Biol Sci Part III: Functions of centrosomes Recent findings on the behaviour of the centrosome at the immunological synapse suggest a critical role for centrosome polarization in controlling the communication between immune cells required to generate an effective immune response. The features observed at the immunological synapse show parallels to centrosome (basal body) polarization seen in cilia and flagella, and the cellular communication that is now known to occur at all of these sites. The Royal Society 2014-09-05 /pmc/articles/PMC4113107/ /pubmed/25047617 http://dx.doi.org/10.1098/rstb.2013.0463 Text en http://creativecommons.org/licenses/by/3.0/ © 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Part III: Functions of centrosomes
Stinchcombe, Jane C.
Griffiths, Gillian M.
Communication, the centrosome and the immunological synapse
title Communication, the centrosome and the immunological synapse
title_full Communication, the centrosome and the immunological synapse
title_fullStr Communication, the centrosome and the immunological synapse
title_full_unstemmed Communication, the centrosome and the immunological synapse
title_short Communication, the centrosome and the immunological synapse
title_sort communication, the centrosome and the immunological synapse
topic Part III: Functions of centrosomes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113107/
https://www.ncbi.nlm.nih.gov/pubmed/25047617
http://dx.doi.org/10.1098/rstb.2013.0463
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