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Function of RasGRP3 in the formation and progression of human breast cancer

INTRODUCTION: Ras guanine nucleotide exchange factors (RasGEFs) mediate the activation of the Ras signaling pathway that is over activated in many human cancers. The RasGRP3, an activator of H-Ras and R-Ras protein exerts oncogenic effects and the overexpression of the protein is observed in numerou...

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Detalles Bibliográficos
Autores principales:	Nagy, Zsuzsanna, Kovács, Ilona, Török, Miklós, Tóth, Dezső, Vereb, György, Buzás, Krisztina, Juhász, István, Blumberg, Peter M, Bíró, Tamás, Czifra, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113147/ https://www.ncbi.nlm.nih.gov/pubmed/24779681 http://dx.doi.org/10.1186/1476-4598-13-96

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