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Isoflurane Reversibly Destabilizes Hippocampal Dendritic Spines by an Actin-Dependent Mechanism

General anesthetics produce a reversible coma-like state through modulation of excitatory and inhibitory synaptic transmission. Recent evidence suggests that anesthetic exposure can also lead to sustained cognitive dysfunction. However, the subcellular effects of anesthetics on the structure of esta...

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Detalles Bibliográficos
Autores principales:	Platholi, Jimcy, Herold, Karl F., Hemmings, Hugh C., Halpain, Shelley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113311/ https://www.ncbi.nlm.nih.gov/pubmed/25068870 http://dx.doi.org/10.1371/journal.pone.0102978

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