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The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children

OBJECTIVE: The controversy that iodized salt may increase the risk of thyroid disorders has been aroused in China during the past decade. Most of studies focused on adult rather than children. We aimed to explore whether iodized salt was associated with an increased risk of thyroid nodule in Chinese...

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Autores principales: Xu, Weimin, Chen, Zexin, Liu, Hui, Huo, Liangliang, Huang, Yangmei, Jin, Xingyi, Deng, Jin, Zhu, Sujuan, Jin, Wen, Zhang, Shanchun, Yu, Yunxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113344/
https://www.ncbi.nlm.nih.gov/pubmed/25068269
http://dx.doi.org/10.1371/journal.pone.0102726
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author Xu, Weimin
Chen, Zexin
Liu, Hui
Huo, Liangliang
Huang, Yangmei
Jin, Xingyi
Deng, Jin
Zhu, Sujuan
Jin, Wen
Zhang, Shanchun
Yu, Yunxian
author_facet Xu, Weimin
Chen, Zexin
Liu, Hui
Huo, Liangliang
Huang, Yangmei
Jin, Xingyi
Deng, Jin
Zhu, Sujuan
Jin, Wen
Zhang, Shanchun
Yu, Yunxian
author_sort Xu, Weimin
collection PubMed
description OBJECTIVE: The controversy that iodized salt may increase the risk of thyroid disorders has been aroused in China during the past decade. Most of studies focused on adult rather than children. We aimed to explore whether iodized salt was associated with an increased risk of thyroid nodule in Chinese children. METHODS: The cross-sectional study was conducted in Hangzhou, China, in 2010. Iodized salt intake, urine iodine concentration (UIC) and thyroid nodule (by ultrasonography) were measured in 3026 children. The associations of iodized salt with thyroid nodule were evaluated using multiple logistic regression models. RESULTS: The prevalence of thyroid nodule was 10.59% among Chinese children. Girls (11.89%) had higher prevalence of thyroid nodule than boys (9.26%). No significant association was observed between type of salt and thyroid nodule in pooled samples, boys and girls, respectively. Similar associations were observed between UIC and thyroid nodule. There was no significant association between milk consumption and thyroid nodule as well. CONCLUSION: The present study indicated that non-iodized salt may not increase the risk of thyroid nodules among Chinese children. Similar associations were observed between milk consumption, UIC and thyroid nodules.
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spelling pubmed-41133442014-08-04 The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children Xu, Weimin Chen, Zexin Liu, Hui Huo, Liangliang Huang, Yangmei Jin, Xingyi Deng, Jin Zhu, Sujuan Jin, Wen Zhang, Shanchun Yu, Yunxian PLoS One Research Article OBJECTIVE: The controversy that iodized salt may increase the risk of thyroid disorders has been aroused in China during the past decade. Most of studies focused on adult rather than children. We aimed to explore whether iodized salt was associated with an increased risk of thyroid nodule in Chinese children. METHODS: The cross-sectional study was conducted in Hangzhou, China, in 2010. Iodized salt intake, urine iodine concentration (UIC) and thyroid nodule (by ultrasonography) were measured in 3026 children. The associations of iodized salt with thyroid nodule were evaluated using multiple logistic regression models. RESULTS: The prevalence of thyroid nodule was 10.59% among Chinese children. Girls (11.89%) had higher prevalence of thyroid nodule than boys (9.26%). No significant association was observed between type of salt and thyroid nodule in pooled samples, boys and girls, respectively. Similar associations were observed between UIC and thyroid nodule. There was no significant association between milk consumption and thyroid nodule as well. CONCLUSION: The present study indicated that non-iodized salt may not increase the risk of thyroid nodules among Chinese children. Similar associations were observed between milk consumption, UIC and thyroid nodules. Public Library of Science 2014-07-28 /pmc/articles/PMC4113344/ /pubmed/25068269 http://dx.doi.org/10.1371/journal.pone.0102726 Text en © 2014 Xu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Xu, Weimin
Chen, Zexin
Liu, Hui
Huo, Liangliang
Huang, Yangmei
Jin, Xingyi
Deng, Jin
Zhu, Sujuan
Jin, Wen
Zhang, Shanchun
Yu, Yunxian
The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title_full The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title_fullStr The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title_full_unstemmed The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title_short The Association of Thyroid Nodule with Non-Iodized Salt among Chinese Children
title_sort association of thyroid nodule with non-iodized salt among chinese children
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113344/
https://www.ncbi.nlm.nih.gov/pubmed/25068269
http://dx.doi.org/10.1371/journal.pone.0102726
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