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Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes
A tessellated fundus is a common characteristic of myopic eyes and is an important clinical marker for the development of retinochoroidal changes. However, the exact cause and significance of tessellated fundi have not been definitively determined. We determined the degree of tessellation in fundi o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113439/ https://www.ncbi.nlm.nih.gov/pubmed/25068821 http://dx.doi.org/10.1371/journal.pone.0103586 |
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author | Yoshihara, Naoya Yamashita, Takehiro Ohno-Matsui, Kyoko Sakamoto, Taiji |
author_facet | Yoshihara, Naoya Yamashita, Takehiro Ohno-Matsui, Kyoko Sakamoto, Taiji |
author_sort | Yoshihara, Naoya |
collection | PubMed |
description | A tessellated fundus is a common characteristic of myopic eyes and is an important clinical marker for the development of retinochoroidal changes. However, the exact cause and significance of tessellated fundi have not been definitively determined. We determined the degree of tessellation in fundi objectively in normal, non-pathological myopic eyes, and correlated the degree of tessellation and the choroidal thickness (CT) and axial length (AL). This was a prospective observational cross sectional study. The eyes were classified subjectively into three groups based on the degree of tessellation observed ophthalmoscopically. Digital color fundus photographs were assessed for the degree of tessellation by ImageJ, an image processing program. Three tessellated fundus indices (TFIs) were calculated and were compared to the three subjectively-determined groups. The subfoveal and nasal CTs were measured in the optical coherence tomographic images. The correlations between the TFIs and the CT were calculated. Additionally, the correlation between the TFIs and the AL was calculated. One hundred right eyes of 100 healthy volunteers (mean age 25.8±3.9 years) were studied. Ophthalmoscopically, 57 eyes were placed in the non-tessellated group, 27 eyes into the weakly tessellated group, and 16 eyes into the strongly tessellated group. There was a significant correlation between the subjective classifications and the TFI values (P<0.05, Kruskal-Wallis test). All of the TFIs were significantly associated with the subfoveal and nasal CT (R = −0.20 to −0.24, P<0.05). The TFIs were not significantly correlated with the ALs. In conclusion, the significant correlation between the subjective and objective classifications of the degree of tessellation indicates that TFIs can be used to classify the degree of tessellation. The results indicate that the differences in the CT account for the degree of tessellation. |
format | Online Article Text |
id | pubmed-4113439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-41134392014-08-04 Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes Yoshihara, Naoya Yamashita, Takehiro Ohno-Matsui, Kyoko Sakamoto, Taiji PLoS One Research Article A tessellated fundus is a common characteristic of myopic eyes and is an important clinical marker for the development of retinochoroidal changes. However, the exact cause and significance of tessellated fundi have not been definitively determined. We determined the degree of tessellation in fundi objectively in normal, non-pathological myopic eyes, and correlated the degree of tessellation and the choroidal thickness (CT) and axial length (AL). This was a prospective observational cross sectional study. The eyes were classified subjectively into three groups based on the degree of tessellation observed ophthalmoscopically. Digital color fundus photographs were assessed for the degree of tessellation by ImageJ, an image processing program. Three tessellated fundus indices (TFIs) were calculated and were compared to the three subjectively-determined groups. The subfoveal and nasal CTs were measured in the optical coherence tomographic images. The correlations between the TFIs and the CT were calculated. Additionally, the correlation between the TFIs and the AL was calculated. One hundred right eyes of 100 healthy volunteers (mean age 25.8±3.9 years) were studied. Ophthalmoscopically, 57 eyes were placed in the non-tessellated group, 27 eyes into the weakly tessellated group, and 16 eyes into the strongly tessellated group. There was a significant correlation between the subjective classifications and the TFI values (P<0.05, Kruskal-Wallis test). All of the TFIs were significantly associated with the subfoveal and nasal CT (R = −0.20 to −0.24, P<0.05). The TFIs were not significantly correlated with the ALs. In conclusion, the significant correlation between the subjective and objective classifications of the degree of tessellation indicates that TFIs can be used to classify the degree of tessellation. The results indicate that the differences in the CT account for the degree of tessellation. Public Library of Science 2014-07-28 /pmc/articles/PMC4113439/ /pubmed/25068821 http://dx.doi.org/10.1371/journal.pone.0103586 Text en © 2014 Yoshihara et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Yoshihara, Naoya Yamashita, Takehiro Ohno-Matsui, Kyoko Sakamoto, Taiji Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title | Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title_full | Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title_fullStr | Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title_full_unstemmed | Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title_short | Objective Analyses of Tessellated Fundi and Significant Correlation between Degree of Tessellation and Choroidal Thickness in Healthy Eyes |
title_sort | objective analyses of tessellated fundi and significant correlation between degree of tessellation and choroidal thickness in healthy eyes |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113439/ https://www.ncbi.nlm.nih.gov/pubmed/25068821 http://dx.doi.org/10.1371/journal.pone.0103586 |
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