Cargando…

High Resolution Melting Analysis: A Rapid and Accurate Method to Detect CALR Mutations

BACKGROUND: The recent discovery of CALR mutations in essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients without JAK2/MPL mutations has emerged as a relevant finding for the molecular diagnosis of these myeloproliferative neoplasms (MPN). We tested the feasibility of high-resolu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bilbao-Sieyro, Cristina, Santana, Guillermo, Moreno, Melania, Torres, Laura, Santana-Lopez, Gonzalo, Rodriguez-Medina, Carlos, Perera, María, Bellosillo, Beatriz, de la Iglesia, Silvia, Molero, Teresa, Gomez-Casares, Maria Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113452/ https://www.ncbi.nlm.nih.gov/pubmed/25068507 http://dx.doi.org/10.1371/journal.pone.0103511

Ejemplares similares

CALR mutation characterization in myeloproliferative neoplasms
por: Bilbao-Sieyro, Cristina, et al.
Publicado: (2016)

Can the Gene Expression Profile of Patients with Acute Myeloid Leukemia Predict Complete Remission Following Induction Therapy?
por: Sánchez-Sosa, Santiago, et al.
Publicado: (2022)

BCL2 Expression at Post-Induction and Complete Remission Impact Outcome in Acute Myeloid Leukemia
por: Bilbao-Sieyro, Cristina, et al.
Publicado: (2020)

Molecular Studies for the Early Detection of Philadelphia-Negative Myeloproliferative Neoplasms
por: Stuckey, Ruth, et al.
Publicado: (2023)

Thrombotic Risk Detection in Patients with Polycythemia Vera: The Predictive Role of DNMT3A/TET2/ASXL1 Mutations
por: Segura-Díaz, Adrián, et al.
Publicado: (2020)

Positive Impact of Eculizumab Therapy on Surgery for Budd-Chiari Syndrome in a Patient with Paroxysmal Nocturnal Hemoglobinuria and a Long-Term History of Thrombosis
por: De-la-Iglesia, Silvia, et al.
Publicado: (2016)

Frequent CALR exon 9 alterations in JAK2 V617F-mutated essential thrombocythemia detected by high-resolution melting analysis
por: Lim, K-H, et al.
Publicado: (2015)

Detection of CALR Mutations Using High Resolution Melting Curve Analysis (HRM-A); Application on a Large Cohort of Greek ET and MF Patients
por: Giannopoulos, Andreas, et al.
Publicado: (2019)

Genetic Testing at Diagnosis Has Prognostic Value in Patients with Chronic Lymphocytic Leukemia including at Early Stages
por: Suárez-Cabrera, Alexia, et al.
Publicado: (2022)

Integration of molecular testing for the personalized management of patients with diffuse large B-cell lymphoma and follicular lymphoma
por: Stuckey, Ruth, et al.
Publicado: (2023)

Predictive indicators of successful tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia
por: Stuckey, Ruth, et al.
Publicado: (2020)

Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis
por: Shide, Kotaro, et al.
Publicado: (2019)

Allelic imbalance in CALR somatic mutagenesis
por: Harutyunyan, A S, et al.
Publicado: (2015)

CALR Mutation Underlying Silent Stroke
por: Faryal, Rehman, et al.
Publicado: (2021)

The Contemporary Approach to CALR-Positive Myeloproliferative Neoplasms
por: Belčič Mikič, Tanja, et al.
Publicado: (2021)

CALR mutations in myeloproliferative neoplasms: An unfolding story
por: Langabeer, Stephen E.
Publicado: (2020)

Bioinformatics analysis for the role of CALR in human cancers
por: Li, Yijun, et al.
Publicado: (2021)

High-Resolution Melting Analysis for accurate detection of BRAF mutations: a systematic review and meta-analysis
por: Chen, Dong, et al.
Publicado: (2014)

Thrombopoietin receptor is required for the oncogenic function of CALR mutants
por: Nivarthi, H, et al.
Publicado: (2016)

Is High Resolution Melting Analysis (HRMA) Accurate for Detection of Human Disease-Associated Mutations? A Meta Analysis
por: Li, Bing-Sheng, et al.
Publicado: (2011)

Presence of Myeloid Mutations in Patients with Chronic Myeloid Leukemia Increases Risk of Cardiovascular Event on Tyrosine Kinase Inhibitor Treatment
por: Stuckey, Ruth, et al.
Publicado: (2023)

EBF1, MYO6 and CALR expression levels predict therapeutic response in diffuse large B-cell lymphomas
por: Turdo, Alice, et al.
Publicado: (2023)

Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia
por: Langabeer, Stephen E., et al.
Publicado: (2016)

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish
por: Lim, K-H, et al.
Publicado: (2016)

Detecting CALR Mutations in Splanchnic Vein Thrombosis: Who and How?
por: Langabeer, Stephen E.
Publicado: (2018)

Splenic mass in a case of CALR‐mutated essential thrombocythemia
por: Imashuku, Shinsaku, et al.
Publicado: (2018)

Sequential evaluation of CALR mutant burden in patients with myeloproliferative neoplasms
por: Cavalloni, Chiara, et al.
Publicado: (2017)

Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm
por: Fraiman, Yarden S, et al.
Publicado: (2016)

Concurrent chronic myeloid leukemia and CALR-mutated myeloproliferative neoplasm
por: Langabeer, Stephen E.
Publicado: (2020)

Effects of CALR-Mutant Type and Burden on the Phenotype of Myeloproliferative Neoplasms
por: Kim, Hyun-Young, et al.
Publicado: (2022)

Retinal neovascularization in the setting of CALR-mutation positive essential thrombocythemia
por: Heydinger, Stanton P, et al.
Publicado: (2023)

A rapid and accurate methylation‐sensitive high‐resolution melting analysis assay for the diagnosis of Prader Willi and Angelman patients
por: Ribeiro Ferreira, Igor, et al.
Publicado: (2019)

A case of congenital dyserythropoietic anemia type IV
por: de‐ la‐ Iglesia‐ Iñigo, Silvia, et al.
Publicado: (2017)

Megakaryocytes, erythropoietic and granulopoietic cells express CAL2 antibody in myeloproliferative neoplasms carrying CALR gene mutations
por: Ali, Hebah, et al.
Publicado: (2020)

Lack of evidence for a causal role of CALR3 in monogenic cardiomyopathy
por: Verhagen, Judith M. A., et al.
Publicado: (2018)

CALR基因阳性的慢性髓性白血病一例
Publicado: (2020)

Primary myelofibrosis with concurrent CALR and MPL mutations: A case report
por: Zhou, Feng-Ping, et al.
Publicado: (2020)

Invasive ductal breast carcinoma preceded by CALR‐positive essential thrombocythemia
por: Ali, Elrazi A., et al.
Publicado: (2021)

Phenotypic correlations of CALR mutation variant allele frequency in patients with myelofibrosis
por: Guglielmelli, Paola, et al.
Publicado: (2023)

A Fast, Sensitive and Accurate High Resolution Melting (HRM) Technology-Based Assay to Screen for Common K-ras Mutations
por: Kramer, D., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_6ium1l9cl01a3mcgj94hf06qv2