Characterization of the Prostate-Specific Antigen (PSA) Catalytic Mechanism: A Pre-Steady-State and Steady-State Study

Prostate-specific antigen (PSA), an enzyme of 30 kDa grouped in the kallikrein family is synthesized to high levels by normal and malignant prostate epithelial cells. Therefore, it is the main biomarker currently used for early diagnosis of prostate cancer. Here, presteady-state and steady-state kin...

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Detalles Bibliográficos
Autores principales: Tomao, Luigi, Sbardella, Diego, Gioia, Magda, Di Masi, Alessandra, Marini, Stefano, Ascenzi, Paolo, Coletta, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113483/
https://www.ncbi.nlm.nih.gov/pubmed/25068395
http://dx.doi.org/10.1371/journal.pone.0102470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113483/
https://www.ncbi.nlm.nih.gov/pubmed/25068395
http://dx.doi.org/10.1371/journal.pone.0102470

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