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Irradiation facilitates the inhibitory effect of the heat shock protein 90 inhibitor NVP-BEP800 on the proliferation of malignant glioblastoma cells through attenuation of the upregulation of heat shock protein 70
The present study aimed to investigate the effect of NVP-BEP800, a novel heat shock protein (Hsp) 90 inhibitor of the 2-aminothieno[2,3-d]pyrimidine class, in combination with radiation on glioblastoma cells. T98G human glioblastoma cells were treated with dimethyl sulfoxide (DMSO), NVP-BEP800, NVP-...
Autores principales: | WU, JIANYUE, WANG, WEIMIN, SHAO, QIN, XIAO, GUOMIN, CHENG, JUN, YUAN, YUNPENG, ZHANG, MEI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113540/ https://www.ncbi.nlm.nih.gov/pubmed/25120620 http://dx.doi.org/10.3892/etm.2014.1800 |
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