Cargando…

EBP50 regulates the apoptosis of pancreatic cancer cells by decreasing the expression levels of Bcl-2

Increasing evidence has demonstrated that ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 (EBP50) is involved in the malignant transformation of numerous human cancers. The present study investigated the involvement of EBP50 overexpression in the tumorigenicity of pancreatic cancer (PC). The re...

Descripción completa

Detalles Bibliográficos
Autores principales:	JI, MENGYAO, YUAN, LEI, LV, XIAOGUANG, DONG, WEIGUO, PENG, XIULAN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113643/ https://www.ncbi.nlm.nih.gov/pubmed/25120624 http://dx.doi.org/10.3892/etm.2014.1831

Ejemplares similares

EBP50 inhibits pancreatic cancer cell growth and invasion by targeting the β-catenin/E-cadherin pathway
por: JI, MENGYAO, et al.
Publicado: (2015)

Clinical significance of EBP50 overexpression assessed by quantum dot analysis in gastric cancer
por: LV, XIAO-GUANG, et al.
Publicado: (2013)

EBP50 induces apoptosis in macrophages by upregulating nitric oxide production to eliminate intracellular Mycobacterium tuberculosis
por: Guo, Yang, et al.
Publicado: (2016)

C/EBPα or C/EBPα oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-κB p50 bound to the bcl-2 and FLIP gene promoters
por: Paz-Priel, I, et al.
Publicado: (2008)

PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli
por: Garbett, Damien, et al.
Publicado: (2012)

The scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent manner
por: Garbett, Damien, et al.
Publicado: (2010)

Temporal and Spatial Regulation of Ezrin-Radixin-Moesin-Binding Phosphoprotein-50-kDa (EBP50) during Embryo Implantation in Mouse Uterus
por: Li, Xing, et al.
Publicado: (2012)

The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics
por: Garbett, Damien, et al.
Publicado: (2013)

Calpain2 Upregulation Regulates EMT-Mediated Pancreatic Cancer Metastasis via the Wnt/β-Catenin Signaling Pathway
por: Peng, Xiulan, et al.
Publicado: (2022)

Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins
por: Zhang, Weiguo, et al.
Publicado: (2005)

A Regulated Complex of the Scaffolding Proteins PDZK1 and EBP50 with Ezrin Contribute to Microvillar Organization
por: LaLonde, David P., et al.
Publicado: (2010)

NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors
por: Georgescu, Maria-Magdalena, et al.
Publicado: (2016)

NHERF1/EBP50 is an organizer of polarity structures and a diagnostic marker in ependymoma
por: Georgescu, Maria-Magdalena, et al.
Publicado: (2015)

C/EBPβ expression decreases in cervical cancer and leads to tumorigenesis
por: Long, Haichen, et al.
Publicado: (2023)

Ras-activated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation
por: Lim, HooiCheng, et al.
Publicado: (2016)

Role of C/EBP-β in Methamphetamine-Mediated Microglial Apoptosis
por: Chen, Xuebing, et al.
Publicado: (2019)

Cell Cycle Dependent Association of EBP50 with Protein Phosphatase 2A in Endothelial Cells
por: Boratkó, Anita, et al.
Publicado: (2012)

EBP50 inhibits EGF-induced breast cancer cell proliferation by blocking EGFR phosphorylation
por: Yao, Wenfang, et al.
Publicado: (2012)

NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway–Driven Intestinal Neoplasia()
por: Georgescu, Maria-Magdalena, et al.
Publicado: (2016)

Epithelial differentiation with microlumen formation in meningioma: diagnostic utility of NHERF1/EBP50 immunohistochemistry
por: Georgescu, Maria-Magdalena, et al.
Publicado: (2018)

Luteolin Induces Apoptosis and Autophagy in Mouse Macrophage ANA-1 Cells via the Bcl-2 Pathway
por: Liao, Yuexia, et al.
Publicado: (2018)

Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family
por: Reczek, David, et al.
Publicado: (1997)

NHERF1/EBP50 controls lactation by establishing basal membrane polarity complexes with prolactin receptor
por: Morales, F C, et al.
Publicado: (2012)

NHERF1/EBP50 as a Target for Modulation of MRP Function in HepG2 Cells
por: Kawase, Atsushi, et al.
Publicado: (2021)

Cotranslational interaction of human EBP50 and ezrin overcomes masked binding site during complex assembly
por: Khan, Krishnendu, et al.
Publicado: (2022)

Targeting BCL-2 regulated apoptosis in cancer
por: Campbell, Kirsteen J., et al.
Publicado: (2018)

Mechanical Strain Downregulates C/EBPβ in MSC and Decreases Endoplasmic Reticulum Stress
por: Styner, Maya, et al.
Publicado: (2012)

C/EBPβ-mediated transcriptional regulation of bcl-xl gene expression in human breast epithelial cells in response to cigarette smoke condensate
por: Connors, Shahnjayla K., et al.
Publicado: (2008)

ErbB3-binding protein EBP1 decreases ErbB2 levels via a transcriptional mechanism
por: GHOSH, ARUNDHATI, et al.
Publicado: (2012)

CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263
por: Huang, Tianlu, et al.
Publicado: (2019)

Intrinsically Disordered Proteins in Bcl-2 Regulated Apoptosis
por: Rautureau, Gilles J. P., et al.
Publicado: (2010)

Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis
por: Ikezawa, Kenji, et al.
Publicado: (2017)

BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis
por: Perez-Serna, Atenea A., et al.
Publicado: (2023)

Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma
por: Nakagawa, Mayu, et al.
Publicado: (2023)

Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels
por: Ma, Shiyang, et al.
Publicado: (2018)

C/EBPα Expression is Partially Regulated by C/EBPβ in Response to DNA Damage and C/EBPα Deficient Fibroblasts Display an Impaired G(1) Checkpoint
por: Ranjan, Rakesh, et al.
Publicado: (2009)

Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis
por: Scheel-Toellner, Dagmar, et al.
Publicado: (2007)

Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
por: Follis, Ariele Viacava, et al.
Publicado: (2018)

Yes-Associated Protein 65 Localizes P62(c-Yes) to the Apical Compartment of Airway Epithelia by Association with Ebp50
por: Mohler, Peter J., et al.
Publicado: (1999)

NHERF1/EBP50 immunoexpression in renal cell carcinomas and oncocytomas with ultrastructural analysis of clear cell renal cell carcinoma
por: Aksionau, Aliaksandr, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ofbkvlnhjkcdp4c67bi7q98e0f