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Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation

Calcifying aponeurotic fibroma (CAF) is a rare, locally aggressive fibroblastic lesion that occurs predominantly in the distal extremities of children and adolescents. In the present study, a case of pathologically proven CAF arising in the right little finger of a 69-year-old woman is presented. Ph...

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Autores principales: NISHIO, JUN, INAMITSU, HIDEAKI, IWASAKI, HIROSHI, HAYASHI, HIROYUKI, NAITO, MASATOSHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113653/
https://www.ncbi.nlm.nih.gov/pubmed/25120611
http://dx.doi.org/10.3892/etm.2014.1838
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author NISHIO, JUN
INAMITSU, HIDEAKI
IWASAKI, HIROSHI
HAYASHI, HIROYUKI
NAITO, MASATOSHI
author_facet NISHIO, JUN
INAMITSU, HIDEAKI
IWASAKI, HIROSHI
HAYASHI, HIROYUKI
NAITO, MASATOSHI
author_sort NISHIO, JUN
collection PubMed
description Calcifying aponeurotic fibroma (CAF) is a rare, locally aggressive fibroblastic lesion that occurs predominantly in the distal extremities of children and adolescents. In the present study, a case of pathologically proven CAF arising in the right little finger of a 69-year-old woman is presented. Physical examination revealed a firm, immobile, non-tender mass. Plain radiographs showed a faintly calcified soft tissue mass without bone involvement and computed tomography scans clearly demonstrated the presence of the lesion. Magnetic resonance imaging revealed that the lesion exhibited low to intermediate signal intensity on T1-weighted images and heterogeneous high signal intensity with small foci of low signal intensity on T2-weighted spectral presaturation with inversion recovery images. Contrast-enhanced fat-suppressed T1-weighted images demonstrated intense heterogeneous enhancement throughout the mass. The patient underwent an excisional biopsy. Histologically, the tumor showed a biphasic pattern, composed of a moderately cellular fibromatosis-like component and irregular calcified areas with polygonal epithelioid cells. There has been no evidence of local recurrence four months following surgery. To the best of our knowledge, this case report describes the oldest patient with this condition.
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spelling pubmed-41136532014-08-12 Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation NISHIO, JUN INAMITSU, HIDEAKI IWASAKI, HIROSHI HAYASHI, HIROYUKI NAITO, MASATOSHI Exp Ther Med Articles Calcifying aponeurotic fibroma (CAF) is a rare, locally aggressive fibroblastic lesion that occurs predominantly in the distal extremities of children and adolescents. In the present study, a case of pathologically proven CAF arising in the right little finger of a 69-year-old woman is presented. Physical examination revealed a firm, immobile, non-tender mass. Plain radiographs showed a faintly calcified soft tissue mass without bone involvement and computed tomography scans clearly demonstrated the presence of the lesion. Magnetic resonance imaging revealed that the lesion exhibited low to intermediate signal intensity on T1-weighted images and heterogeneous high signal intensity with small foci of low signal intensity on T2-weighted spectral presaturation with inversion recovery images. Contrast-enhanced fat-suppressed T1-weighted images demonstrated intense heterogeneous enhancement throughout the mass. The patient underwent an excisional biopsy. Histologically, the tumor showed a biphasic pattern, composed of a moderately cellular fibromatosis-like component and irregular calcified areas with polygonal epithelioid cells. There has been no evidence of local recurrence four months following surgery. To the best of our knowledge, this case report describes the oldest patient with this condition. D.A. Spandidos 2014-09 2014-07-11 /pmc/articles/PMC4113653/ /pubmed/25120611 http://dx.doi.org/10.3892/etm.2014.1838 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
NISHIO, JUN
INAMITSU, HIDEAKI
IWASAKI, HIROSHI
HAYASHI, HIROYUKI
NAITO, MASATOSHI
Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title_full Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title_fullStr Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title_full_unstemmed Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title_short Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation
title_sort calcifying aponeurotic fibroma of the finger in an elderly patient: ct and mri findings with pathologic correlation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113653/
https://www.ncbi.nlm.nih.gov/pubmed/25120611
http://dx.doi.org/10.3892/etm.2014.1838
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