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Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool
Staphylococcus aureus is a common and often virulent pathogen in humans. This bacterium is widespread, being present on the skin and in the nose of healthy people. Staphylococcus aureus can cause infections with severe outcomes ranging from pustules to sepsis and death. The introduction of antibioti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113783/ https://www.ncbi.nlm.nih.gov/pubmed/24988520 http://dx.doi.org/10.3390/v6072551 |
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author | Kaźmierczak, Zuzanna Górski, Andrzej Dąbrowska, Krystyna |
author_facet | Kaźmierczak, Zuzanna Górski, Andrzej Dąbrowska, Krystyna |
author_sort | Kaźmierczak, Zuzanna |
collection | PubMed |
description | Staphylococcus aureus is a common and often virulent pathogen in humans. This bacterium is widespread, being present on the skin and in the nose of healthy people. Staphylococcus aureus can cause infections with severe outcomes ranging from pustules to sepsis and death. The introduction of antibiotics led to a general belief that the problem of bacterial infections would be solved. Nonetheless, pathogens including staphylococci have evolved mechanisms of drug resistance. Among current attempts to address this problem, phage therapy offers a promising alternative to combat staphylococcal infections. Here, we present an overview of current knowledge on staphylococcal infections and bacteriophages able to kill Staphylococcus, including experimental studies and available data on their clinical use. |
format | Online Article Text |
id | pubmed-4113783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-41137832014-07-29 Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool Kaźmierczak, Zuzanna Górski, Andrzej Dąbrowska, Krystyna Viruses Review Staphylococcus aureus is a common and often virulent pathogen in humans. This bacterium is widespread, being present on the skin and in the nose of healthy people. Staphylococcus aureus can cause infections with severe outcomes ranging from pustules to sepsis and death. The introduction of antibiotics led to a general belief that the problem of bacterial infections would be solved. Nonetheless, pathogens including staphylococci have evolved mechanisms of drug resistance. Among current attempts to address this problem, phage therapy offers a promising alternative to combat staphylococcal infections. Here, we present an overview of current knowledge on staphylococcal infections and bacteriophages able to kill Staphylococcus, including experimental studies and available data on their clinical use. MDPI 2014-07-01 /pmc/articles/PMC4113783/ /pubmed/24988520 http://dx.doi.org/10.3390/v6072551 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Kaźmierczak, Zuzanna Górski, Andrzej Dąbrowska, Krystyna Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title | Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title_full | Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title_fullStr | Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title_full_unstemmed | Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title_short | Facing Antibiotic Resistance: Staphylococcus aureus Phages as a Medical Tool |
title_sort | facing antibiotic resistance: staphylococcus aureus phages as a medical tool |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113783/ https://www.ncbi.nlm.nih.gov/pubmed/24988520 http://dx.doi.org/10.3390/v6072551 |
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