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New Hippolide Derivatives with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Marine Sponge Hippospongia lachne

Five new sesterterpenoids, compounds 1–5, have been isolated from the sponge Hippospongia lachne off Yongxing Island in the South China Sea. The structures of compounds 1–5 were elucidated through extensive spectroscopic analysis, including HRMS, 1D, and 2D NMR experiments. The stereochemistry, incl...

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Detalles Bibliográficos
Autores principales: Piao, Shu-Juan, Jiao, Wei-Hua, Yang, Fan, Yi, Yang-Hua, Di, Ying-Tong, Han, Bing-Nan, Lin, Hou-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113817/
https://www.ncbi.nlm.nih.gov/pubmed/25007159
http://dx.doi.org/10.3390/md12074096