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Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac

Voltage-gated sodium channels mediate the initiation and propagation of action potentials in excitable cells. Transmembrane segment S4 of voltage-gated sodium channels resides in a gating pore where it senses the membrane potential and controls channel gating. Substitution of individual S4 arginine...

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Detalles Bibliográficos
Autores principales: Gamal El-Din, Tamer M., Scheuer, Todd, Catterall, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113903/
https://www.ncbi.nlm.nih.gov/pubmed/25070432
http://dx.doi.org/10.1085/jgp.201411210

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