18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload–induced maladaptive cardiac remodeling

N-3 polyunsaturated fatty acids (PUFAs) have potential cardiovascular benefit, although the mechanisms underlying this effect remain poorly understood. Fat-1 transgenic mice expressing Caenorhabditis elegans n-3 fatty acid desaturase, which is capable of producing n-3 PUFAs from n-6 PUFAs, exhibited...

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Detalles Bibliográficos
Autores principales: Endo, Jin, Sano, Motoaki, Isobe, Yosuke, Fukuda, Keiichi, Kang, Jing X., Arai, Hiroyuki, Arita, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113943/
https://www.ncbi.nlm.nih.gov/pubmed/25049337
http://dx.doi.org/10.1084/jem.20132011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113943/
https://www.ncbi.nlm.nih.gov/pubmed/25049337
http://dx.doi.org/10.1084/jem.20132011

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