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Extensive Loculated Ascites in Hepatic Amyloidosis

CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension,...

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Autores principales: Buppajarntham, Saranya, Kue-A-Pai, Pongsathorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114014/
https://www.ncbi.nlm.nih.gov/pubmed/25077085
http://dx.doi.org/10.4103/1947-2714.136923
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author Buppajarntham, Saranya
Kue-A-Pai, Pongsathorn
author_facet Buppajarntham, Saranya
Kue-A-Pai, Pongsathorn
author_sort Buppajarntham, Saranya
collection PubMed
description CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension, and gastrointestinal bleeding from esophageal varices were reported in literature. CASE REPORT: A 42-year-old man with end-stage renal disease on hemodialysis and recent small bowel obstruction presented with chronic abdominal pain. Computed tomography of abdomen and pelvis showed extensive loculated ascites and multiple small bowel loops tethered to adhesions and hepatomegaly. Finally, hepatic venography and liver biopsy confirmed hepatic amyloidosis with portal hypertension. The patient was waiting for liver transplant for definite treatment. CONCLUSION: We report a rare case of hepatic amyloidosis with prior small bowel obstruction presented with extensive loculated ascites and multiple small bowel loops tethered to adhesions.
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spelling pubmed-41140142014-07-30 Extensive Loculated Ascites in Hepatic Amyloidosis Buppajarntham, Saranya Kue-A-Pai, Pongsathorn N Am J Med Sci Case Report CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension, and gastrointestinal bleeding from esophageal varices were reported in literature. CASE REPORT: A 42-year-old man with end-stage renal disease on hemodialysis and recent small bowel obstruction presented with chronic abdominal pain. Computed tomography of abdomen and pelvis showed extensive loculated ascites and multiple small bowel loops tethered to adhesions and hepatomegaly. Finally, hepatic venography and liver biopsy confirmed hepatic amyloidosis with portal hypertension. The patient was waiting for liver transplant for definite treatment. CONCLUSION: We report a rare case of hepatic amyloidosis with prior small bowel obstruction presented with extensive loculated ascites and multiple small bowel loops tethered to adhesions. Medknow Publications & Media Pvt Ltd 2014-07 /pmc/articles/PMC4114014/ /pubmed/25077085 http://dx.doi.org/10.4103/1947-2714.136923 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Buppajarntham, Saranya
Kue-A-Pai, Pongsathorn
Extensive Loculated Ascites in Hepatic Amyloidosis
title Extensive Loculated Ascites in Hepatic Amyloidosis
title_full Extensive Loculated Ascites in Hepatic Amyloidosis
title_fullStr Extensive Loculated Ascites in Hepatic Amyloidosis
title_full_unstemmed Extensive Loculated Ascites in Hepatic Amyloidosis
title_short Extensive Loculated Ascites in Hepatic Amyloidosis
title_sort extensive loculated ascites in hepatic amyloidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114014/
https://www.ncbi.nlm.nih.gov/pubmed/25077085
http://dx.doi.org/10.4103/1947-2714.136923
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