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Extensive Loculated Ascites in Hepatic Amyloidosis
CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114014/ https://www.ncbi.nlm.nih.gov/pubmed/25077085 http://dx.doi.org/10.4103/1947-2714.136923 |
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author | Buppajarntham, Saranya Kue-A-Pai, Pongsathorn |
author_facet | Buppajarntham, Saranya Kue-A-Pai, Pongsathorn |
author_sort | Buppajarntham, Saranya |
collection | PubMed |
description | CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension, and gastrointestinal bleeding from esophageal varices were reported in literature. CASE REPORT: A 42-year-old man with end-stage renal disease on hemodialysis and recent small bowel obstruction presented with chronic abdominal pain. Computed tomography of abdomen and pelvis showed extensive loculated ascites and multiple small bowel loops tethered to adhesions and hepatomegaly. Finally, hepatic venography and liver biopsy confirmed hepatic amyloidosis with portal hypertension. The patient was waiting for liver transplant for definite treatment. CONCLUSION: We report a rare case of hepatic amyloidosis with prior small bowel obstruction presented with extensive loculated ascites and multiple small bowel loops tethered to adhesions. |
format | Online Article Text |
id | pubmed-4114014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41140142014-07-30 Extensive Loculated Ascites in Hepatic Amyloidosis Buppajarntham, Saranya Kue-A-Pai, Pongsathorn N Am J Med Sci Case Report CONTEXT: Amyloidosis is a disease of extracellular deposition of misfolded proteinaceous subunits, which could be systemic or localized disease. Though hepatic amyloidosis was not uncommon in autopsy series, most cases of hepatic amyloidosis were asymptomatic. Ascites, jaundice, portal hypertension, and gastrointestinal bleeding from esophageal varices were reported in literature. CASE REPORT: A 42-year-old man with end-stage renal disease on hemodialysis and recent small bowel obstruction presented with chronic abdominal pain. Computed tomography of abdomen and pelvis showed extensive loculated ascites and multiple small bowel loops tethered to adhesions and hepatomegaly. Finally, hepatic venography and liver biopsy confirmed hepatic amyloidosis with portal hypertension. The patient was waiting for liver transplant for definite treatment. CONCLUSION: We report a rare case of hepatic amyloidosis with prior small bowel obstruction presented with extensive loculated ascites and multiple small bowel loops tethered to adhesions. Medknow Publications & Media Pvt Ltd 2014-07 /pmc/articles/PMC4114014/ /pubmed/25077085 http://dx.doi.org/10.4103/1947-2714.136923 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Buppajarntham, Saranya Kue-A-Pai, Pongsathorn Extensive Loculated Ascites in Hepatic Amyloidosis |
title | Extensive Loculated Ascites in Hepatic Amyloidosis |
title_full | Extensive Loculated Ascites in Hepatic Amyloidosis |
title_fullStr | Extensive Loculated Ascites in Hepatic Amyloidosis |
title_full_unstemmed | Extensive Loculated Ascites in Hepatic Amyloidosis |
title_short | Extensive Loculated Ascites in Hepatic Amyloidosis |
title_sort | extensive loculated ascites in hepatic amyloidosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114014/ https://www.ncbi.nlm.nih.gov/pubmed/25077085 http://dx.doi.org/10.4103/1947-2714.136923 |
work_keys_str_mv | AT buppajarnthamsaranya extensiveloculatedascitesinhepaticamyloidosis AT kueapaipongsathorn extensiveloculatedascitesinhepaticamyloidosis |