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New strategies with anti-IgE in allergic diseases

IgE has long been known as a therapeutic target for allergic disease, but the difficulty has been in selecting agents that don't trigger cross linkage of IgE when bound to its high affinity receptor (FceR1) on mast cells and basophils. By “designing” a monoclonal antibody (mAb) which targets th...

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Detalles Bibliográficos
Autor principal: Holgate, Stephen T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114087/
https://www.ncbi.nlm.nih.gov/pubmed/25097719
http://dx.doi.org/10.1186/1939-4551-7-17

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