Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case–control study of African children

BACKGROUND: Severe and fatal malaria are associated with dysregulated host inflammatory responses to infection. Chitinase 3-like 1 (CHI3L1) is a secreted glycoprotein implicated in regulating immune responses. Expression and function of CHI3L1 in malaria infection were investigated. METHODS: Plasma...

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Detalles Bibliográficos
Autores principales: Erdman, Laura K, Petes, Carlene, Lu, Ziyue, Dhabangi, Aggrey, Musoke, Charles, Cserti-Gazdewich, Christine M, Lee, Chun Geun, Liles, Wayne Conrad, Elias, Jack A, Kain, Kevin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114103/
https://www.ncbi.nlm.nih.gov/pubmed/25047113
http://dx.doi.org/10.1186/1475-2875-13-279

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