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Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling
INTRODUCTION: The androgen receptor (AR) is the most highly expressed steroid receptor in breast cancer with 75–95% of estrogen receptor (ER)-positive and 40–70% of ER-negative breast cancers expressing AR. Though historically breast cancers were treated with steroidal androgens, their use fell from...
Autores principales: | Narayanan, Ramesh, Ahn, Sunjoo, Cheney, Misty D., Yepuru, Muralimohan, Miller, Duane D., Steiner, Mitchell S., Dalton, James T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114483/ https://www.ncbi.nlm.nih.gov/pubmed/25072326 http://dx.doi.org/10.1371/journal.pone.0103202 |
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