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The antibacterial toxin colicin N binds to the inner core of lipopolysaccharide and close to its translocator protein
Colicins are a diverse family of large antibacterial protein toxins, secreted by and active against Escherichia coli and must cross their target cell's outer membrane barrier to kill. To achieve this, most colicins require an abundant porin (e.g. OmpF) plus a low‐copy‐number, high‐affinity, out...
Autores principales: | Johnson, Christopher L., Ridley, Helen, Marchetti, Roberta, Silipo, Alba, Griffin, David C., Crawford, Lucy, Bonev, Boyan, Molinaro, Antonio, Lakey, Jeremy H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Scientific Publications
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114557/ https://www.ncbi.nlm.nih.gov/pubmed/24589252 http://dx.doi.org/10.1111/mmi.12568 |
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