TGF-β Signaling Initiated in Dendritic Cells Instructs Suppressive Effects on Th17 Differentiation at the Site of Neuroinflammation

While the role of Transforming Growth Factor β (TGF-β) as an intrinsic pathway has been well established in driving de novo differentiation of Th17 cells, no study has directly assessed the capacity of TGF-β signaling initiated within dendritic cells (DCs) to regulate Th17 differentiation. The centr...

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Detalles Bibliográficos
Autores principales: Speck, Suzanne, Lim, James, Shelake, Sagar, Matka, Marsel, Stoddard, Jonathan, Farr, Alexander, Kuchroo, Vijay, Laouar, Yasmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114567/
https://www.ncbi.nlm.nih.gov/pubmed/25072375
http://dx.doi.org/10.1371/journal.pone.0102390

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