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10058-F4, a c-Myc inhibitor, markedly increases valproic acid-induced cell death in Jurkat and CCRF-CEM T-lymphoblastic leukemia cells

Adult T-cell acute lymphoblastic leukemia (T-ALL) has a poor prognosis. Although it has been found that activation of Notch1 signaling occurs in >50% T-ALL patients, γ-secretase inhibitors that target Notch1 signaling are of limited efficacy. However, c-Myc is an important direct target of Notch1...

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Detalles Bibliográficos
Autores principales:	MU, QITIAN, MA, QIULING, LU, SHASHA, ZHANG, TING, YU, MENGXIA, HUANG, XIN, CHEN, JIAN, JIN, JIE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114592/ https://www.ncbi.nlm.nih.gov/pubmed/25120723 http://dx.doi.org/10.3892/ol.2014.2277

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