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Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns

Radiation therapy is one of the cornerstones of modern multidisciplinary cancer treatment. Normal tissue tolerance is critical as radiation-induced side effects may compromise organ function and quality of life. The importance of normal tissue research is reflected by the large number of scientific...

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Autores principales: NIEDER, CARSTEN, ANDRATSCHKE, NICOLAUS H., GROSU, ANCA L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114634/
https://www.ncbi.nlm.nih.gov/pubmed/25120644
http://dx.doi.org/10.3892/ol.2014.2252
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author NIEDER, CARSTEN
ANDRATSCHKE, NICOLAUS H.
GROSU, ANCA L.
author_facet NIEDER, CARSTEN
ANDRATSCHKE, NICOLAUS H.
GROSU, ANCA L.
author_sort NIEDER, CARSTEN
collection PubMed
description Radiation therapy is one of the cornerstones of modern multidisciplinary cancer treatment. Normal tissue tolerance is critical as radiation-induced side effects may compromise organ function and quality of life. The importance of normal tissue research is reflected by the large number of scientific articles, which have been published between 2006 and 2010. The present study identified important areas of research as well as seminal publications. The article citation rate is among the potential indicators of scientific impact. Highly cited articles, arbitrarily defined as those with ≥15 citations, were identified via a systematic search of the citation database, Scopus. Up to 608 articles per year were published between 2006 and 2010, however, <10% of publications in each year accumulated ≥15 citations. This figure is notably low, when compared with other oncology studies. A large variety of preclinical and clinical topics, including toxicity prediction, the dose-volume relationship and radioprotectors, accumulated ≥15 citations. However, clinical prevention or mitigation studies were underrepresented. The following conclusion may be drawn from the present study; despite the improved technology that has resulted in superior dose distribution, clinical prevention or mitigation studies are critical and must receive higher priority, funding and attention.
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spelling pubmed-41146342014-08-12 Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns NIEDER, CARSTEN ANDRATSCHKE, NICOLAUS H. GROSU, ANCA L. Oncol Lett Articles Radiation therapy is one of the cornerstones of modern multidisciplinary cancer treatment. Normal tissue tolerance is critical as radiation-induced side effects may compromise organ function and quality of life. The importance of normal tissue research is reflected by the large number of scientific articles, which have been published between 2006 and 2010. The present study identified important areas of research as well as seminal publications. The article citation rate is among the potential indicators of scientific impact. Highly cited articles, arbitrarily defined as those with ≥15 citations, were identified via a systematic search of the citation database, Scopus. Up to 608 articles per year were published between 2006 and 2010, however, <10% of publications in each year accumulated ≥15 citations. This figure is notably low, when compared with other oncology studies. A large variety of preclinical and clinical topics, including toxicity prediction, the dose-volume relationship and radioprotectors, accumulated ≥15 citations. However, clinical prevention or mitigation studies were underrepresented. The following conclusion may be drawn from the present study; despite the improved technology that has resulted in superior dose distribution, clinical prevention or mitigation studies are critical and must receive higher priority, funding and attention. D.A. Spandidos 2014-09 2014-06-13 /pmc/articles/PMC4114634/ /pubmed/25120644 http://dx.doi.org/10.3892/ol.2014.2252 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
NIEDER, CARSTEN
ANDRATSCHKE, NICOLAUS H.
GROSU, ANCA L.
Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title_full Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title_fullStr Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title_full_unstemmed Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title_short Normal tissue studies in radiation oncology: A systematic review of highly cited articles and citation patterns
title_sort normal tissue studies in radiation oncology: a systematic review of highly cited articles and citation patterns
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114634/
https://www.ncbi.nlm.nih.gov/pubmed/25120644
http://dx.doi.org/10.3892/ol.2014.2252
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