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Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report
Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of the liver, and its definitive diagnosis is completely dependent on histopathological verification. In the present study, we report the case of a patient whose percutaneous liver biopsy failed to reveal a diagnosis of HEH, twi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114635/ https://www.ncbi.nlm.nih.gov/pubmed/25120715 http://dx.doi.org/10.3892/ol.2014.2308 |
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author | DENG, YILEI ZHOU, YONG CHENG, NANSHENG |
author_facet | DENG, YILEI ZHOU, YONG CHENG, NANSHENG |
author_sort | DENG, YILEI |
collection | PubMed |
description | Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of the liver, and its definitive diagnosis is completely dependent on histopathological verification. In the present study, we report the case of a patient whose percutaneous liver biopsy failed to reveal a diagnosis of HEH, twice, and who was ultimately diagnosed by laparoscopic liver biopsy. The patient was a 42-year-old female with mild right upper quadrant discomfort. Ultrasonography and magnetic resonance imaging showed multiple mass lesions scattered throughout the liver, but no evidence of extrahepatic diseases. The initial laboratory tests included liver function tests and tumor markers were within normal limits. Subsequently, two, ultrasound (US)-guided liver biopsies from the liver lesion were performed using an 18-gauge needle, and both of these showed massive hepatocellular necrosis. To obtain adequate tissue samples for histological examination, the patient underwent laparoscopic liver biopsy. The overall immunohistochemical findings supported the diagnosis of HEH. In the present case, two, US-guided percutaneous liver biopsies failed to diagnose HEH, and laparoscopic liver biopsy was safely performed to obtained adequate specimens for analysis. Although this method is not the preferred technique and has certain disadvantages, it is considered to be a useful and minimally invasive approach for liver lesions when other less-invasive diagnostic modalities fail or are difficult to be performed. |
format | Online Article Text |
id | pubmed-4114635 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-41146352014-08-12 Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report DENG, YILEI ZHOU, YONG CHENG, NANSHENG Oncol Lett Articles Hepatic epithelioid hemangioendothelioma (HEH) is a rare vascular tumor of the liver, and its definitive diagnosis is completely dependent on histopathological verification. In the present study, we report the case of a patient whose percutaneous liver biopsy failed to reveal a diagnosis of HEH, twice, and who was ultimately diagnosed by laparoscopic liver biopsy. The patient was a 42-year-old female with mild right upper quadrant discomfort. Ultrasonography and magnetic resonance imaging showed multiple mass lesions scattered throughout the liver, but no evidence of extrahepatic diseases. The initial laboratory tests included liver function tests and tumor markers were within normal limits. Subsequently, two, ultrasound (US)-guided liver biopsies from the liver lesion were performed using an 18-gauge needle, and both of these showed massive hepatocellular necrosis. To obtain adequate tissue samples for histological examination, the patient underwent laparoscopic liver biopsy. The overall immunohistochemical findings supported the diagnosis of HEH. In the present case, two, US-guided percutaneous liver biopsies failed to diagnose HEH, and laparoscopic liver biopsy was safely performed to obtained adequate specimens for analysis. Although this method is not the preferred technique and has certain disadvantages, it is considered to be a useful and minimally invasive approach for liver lesions when other less-invasive diagnostic modalities fail or are difficult to be performed. D.A. Spandidos 2014-09 2014-07-02 /pmc/articles/PMC4114635/ /pubmed/25120715 http://dx.doi.org/10.3892/ol.2014.2308 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles DENG, YILEI ZHOU, YONG CHENG, NANSHENG Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title | Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title_full | Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title_fullStr | Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title_full_unstemmed | Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title_short | Laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: A case report |
title_sort | laparoscopic liver biopsy in the diagnosis of hepatic epithelioid hemangioendothelioma: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114635/ https://www.ncbi.nlm.nih.gov/pubmed/25120715 http://dx.doi.org/10.3892/ol.2014.2308 |
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