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Transcript assisted phosphodiester bond hydrolysis by eukaryotic RNA polymerase II
Hydrolysis of the phosphodiester bonds of the transcript by bacterial RNA polymerase is assisted by 3′NMP of the RNA. Here we provide evidence that this mechanism is also involved in RNA cleavage by eukaryotic RNA polymerase II, suggesting that transcript assisted hydrolysis has emerged before diver...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114657/ https://www.ncbi.nlm.nih.gov/pubmed/24270513 http://dx.doi.org/10.4161/trns.27062 |