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Zinc'ing down RNA polymerase I
Most RNA polymerases contain zinc, yet the precise function of zinc and its influence of polymerases stability are unknown. A recent study provides evidence that zinc levels control the stability of RNA polymerase I in vivo and that the enzyme might serve as a zinc reservoir for other proteins.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114658/ https://www.ncbi.nlm.nih.gov/pubmed/24135703 http://dx.doi.org/10.4161/trns.26594 |
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author | Chanfreau, Guillaume F |
author_facet | Chanfreau, Guillaume F |
author_sort | Chanfreau, Guillaume F |
collection | PubMed |
description | Most RNA polymerases contain zinc, yet the precise function of zinc and its influence of polymerases stability are unknown. A recent study provides evidence that zinc levels control the stability of RNA polymerase I in vivo and that the enzyme might serve as a zinc reservoir for other proteins. |
format | Online Article Text |
id | pubmed-4114658 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-41146582014-07-30 Zinc'ing down RNA polymerase I Chanfreau, Guillaume F Transcription Point of View Most RNA polymerases contain zinc, yet the precise function of zinc and its influence of polymerases stability are unknown. A recent study provides evidence that zinc levels control the stability of RNA polymerase I in vivo and that the enzyme might serve as a zinc reservoir for other proteins. Landes Bioscience 2013-09-01 2013-09-27 /pmc/articles/PMC4114658/ /pubmed/24135703 http://dx.doi.org/10.4161/trns.26594 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Point of View Chanfreau, Guillaume F Zinc'ing down RNA polymerase I |
title | Zinc'ing down RNA polymerase I |
title_full | Zinc'ing down RNA polymerase I |
title_fullStr | Zinc'ing down RNA polymerase I |
title_full_unstemmed | Zinc'ing down RNA polymerase I |
title_short | Zinc'ing down RNA polymerase I |
title_sort | zinc'ing down rna polymerase i |
topic | Point of View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114658/ https://www.ncbi.nlm.nih.gov/pubmed/24135703 http://dx.doi.org/10.4161/trns.26594 |
work_keys_str_mv | AT chanfreauguillaumef zincingdownrnapolymerasei |