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Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma

The RAS/RAF and PI3K/PTEN signaling pathways play central roles in hepatocarcinogenesis. KRAS, NRAS, HRAS, BRAF, PIK3CA, PIK3R1 and PTEN are key cancer-related genes in the RAS/RAF and PI3K/PTEN signaling pathways. Genetic alterations in these genes often lead to the dysregulation of the two cascade...

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Detalles Bibliográficos
Autores principales:	HOU, WENMIN, LIU, JIBIN, CHEN, PEIZHAN, WANG, HUI, YE, BANG-CE, QIANG, FULIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114707/ https://www.ncbi.nlm.nih.gov/pubmed/25120700 http://dx.doi.org/10.3892/ol.2014.2253

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