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Short Term Morphine Exposure In Vitro Alters Proliferation and Differentiation of Neural Progenitor Cells and Promotes Apoptosis via Mu Receptors

BACKGROUND: Chronic morphine treatment inhibits neural progenitor cell (NPC) progression and negatively effects hippocampal neurogenesis. However, the effect of acute opioid treatment on cell development and its influence on NPC differentiation and proliferation in vitro is unknown. We aim to invest...

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Detalles Bibliográficos
Autores principales: Willner, Dafna, Cohen-Yeshurun, Ayelet, Avidan, Alexander, Ozersky, Vladislav, Shohami, Esther, Leker, Ronen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114742/
https://www.ncbi.nlm.nih.gov/pubmed/25072277
http://dx.doi.org/10.1371/journal.pone.0103043