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Short Term Morphine Exposure In Vitro Alters Proliferation and Differentiation of Neural Progenitor Cells and Promotes Apoptosis via Mu Receptors
BACKGROUND: Chronic morphine treatment inhibits neural progenitor cell (NPC) progression and negatively effects hippocampal neurogenesis. However, the effect of acute opioid treatment on cell development and its influence on NPC differentiation and proliferation in vitro is unknown. We aim to invest...
Autores principales: | Willner, Dafna, Cohen-Yeshurun, Ayelet, Avidan, Alexander, Ozersky, Vladislav, Shohami, Esther, Leker, Ronen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114742/ https://www.ncbi.nlm.nih.gov/pubmed/25072277 http://dx.doi.org/10.1371/journal.pone.0103043 |
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