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A PU.1 Suppressive Target Gene, Metallothionein 1G, Inhibits Retinoic Acid-Induced NB4 Cell Differentiation

We recently revealed that myeloid master regulator SPI1/PU.1 directly represses metallothionein (MT) 1G through its epigenetic activity of PU.1, but the functions of MT1G in myeloid differentiation remain unknown. To clarify this, we established MT1G-overexpressing acute promyelocytic leukemia NB4 (...

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Detalles Bibliográficos
Autores principales:	Hirako, Naomi, Nakano, Hiroko, Takahashi, Shinichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114787/ https://www.ncbi.nlm.nih.gov/pubmed/25072246 http://dx.doi.org/10.1371/journal.pone.0103282

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