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Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is a highly aggressive form of breast cancer resistant to many common treatments. In this study, we compared the effects of 12 phytochemical drugs on four cancer cell lines, and noticed that Cucurbitacin E (CuE) significantly inhibited TNBC cell growth by inducin...

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Detalles Bibliográficos
Autores principales: Kong, Yanjie, Chen, Jianchao, Zhou, Zhongmei, Xia, Houjun, Qiu, Ming-Hua, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114842/
https://www.ncbi.nlm.nih.gov/pubmed/25072848
http://dx.doi.org/10.1371/journal.pone.0103760

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