Improved Efficacy and Reduced Toxicity of Doxorubicin Encapsulated in Sulfatide-Containing Nanoliposome in a Glioma Model

As a glycosphingolipid that can bind to several extracellular matrix proteins, sulfatide has the potential to become an effective targeting agent for tumors overexpressing tenasin-C in their microenvironment. To overcome the dose-limiting toxicity of doxorubicin (DOX), a sulfatide-containing nanolip...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jia, Shigdar, Sarah, Fang, Ding Zhi, Xiang, Dognxi, Wei, Ming Q., Danks, Andrew, Kong, Lingxue, Li, Lianghong, Qiao, Liang, Duan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114873/
https://www.ncbi.nlm.nih.gov/pubmed/25072631
http://dx.doi.org/10.1371/journal.pone.0103736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114873/
https://www.ncbi.nlm.nih.gov/pubmed/25072631
http://dx.doi.org/10.1371/journal.pone.0103736

Ejemplares similares