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Molecular epidemiology of rabies virus in Poland

The paper describes a phylogenetic study of 58 Polish isolates of rabies virus collected between 1992 and 2010. Sequences of the nucleoprotein (N) and glycoprotein (G) genes approximately 600 bp long were compared with reference sequences (GenBank) of European rabies viruses from neighbouring countr...

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Autores principales: Orłowska, Anna, Żmudziński, Jan Franciszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115184/
https://www.ncbi.nlm.nih.gov/pubmed/24627096
http://dx.doi.org/10.1007/s00705-014-2045-z
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author Orłowska, Anna
Żmudziński, Jan Franciszek
author_facet Orłowska, Anna
Żmudziński, Jan Franciszek
author_sort Orłowska, Anna
collection PubMed
description The paper describes a phylogenetic study of 58 Polish isolates of rabies virus collected between 1992 and 2010. Sequences of the nucleoprotein (N) and glycoprotein (G) genes approximately 600 bp long were compared with reference sequences (GenBank) of European rabies viruses from neighbouring countries. The study confirmed a very high level of homology (94.4–100 %) of the Polish rabies virus strains irrespective of the date of isolation. Two variants of rabies virus: NEE (Northeastern Europe variant) and CE (Central Europe variant), depending on the geographical place of isolation, were circulating in Poland from 1992 to 2010. The Polish rabies virus isolates showed high similarity to European RABV strains, especially those collected in Ukraine and Romania. They were clearly different from vaccine strains SAD B19 and SAD Bern, which have been used for oral vaccination of foxes against rabies in Poland since 1993.
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spelling pubmed-41151842014-08-04 Molecular epidemiology of rabies virus in Poland Orłowska, Anna Żmudziński, Jan Franciszek Arch Virol Original Article The paper describes a phylogenetic study of 58 Polish isolates of rabies virus collected between 1992 and 2010. Sequences of the nucleoprotein (N) and glycoprotein (G) genes approximately 600 bp long were compared with reference sequences (GenBank) of European rabies viruses from neighbouring countries. The study confirmed a very high level of homology (94.4–100 %) of the Polish rabies virus strains irrespective of the date of isolation. Two variants of rabies virus: NEE (Northeastern Europe variant) and CE (Central Europe variant), depending on the geographical place of isolation, were circulating in Poland from 1992 to 2010. The Polish rabies virus isolates showed high similarity to European RABV strains, especially those collected in Ukraine and Romania. They were clearly different from vaccine strains SAD B19 and SAD Bern, which have been used for oral vaccination of foxes against rabies in Poland since 1993. Springer Vienna 2014-03-14 2014 /pmc/articles/PMC4115184/ /pubmed/24627096 http://dx.doi.org/10.1007/s00705-014-2045-z Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Orłowska, Anna
Żmudziński, Jan Franciszek
Molecular epidemiology of rabies virus in Poland
title Molecular epidemiology of rabies virus in Poland
title_full Molecular epidemiology of rabies virus in Poland
title_fullStr Molecular epidemiology of rabies virus in Poland
title_full_unstemmed Molecular epidemiology of rabies virus in Poland
title_short Molecular epidemiology of rabies virus in Poland
title_sort molecular epidemiology of rabies virus in poland
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115184/
https://www.ncbi.nlm.nih.gov/pubmed/24627096
http://dx.doi.org/10.1007/s00705-014-2045-z
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