Cargando…
Unheard voices: outcomes of tertiary care for treatment-refractory psychosis
Aims and method In up to a quarter of patients, schizophrenia is resistant to standard treatments. We undertook a naturalistic study of 153 patients treated in the tertiary referral in-patient unit of the National Psychosis Service based at the Maudsley Hospital in London. A retrospective analysis o...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal College of Psychiatrists
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115394/ https://www.ncbi.nlm.nih.gov/pubmed/25237502 http://dx.doi.org/10.1192/pb.bp.112.042598 |
_version_ | 1782328541027762176 |
---|---|
author | Sarkar, S. Neil Tracy, Derek K. Fernandez, Maria-Jesus Mateos Nalesnik, Natasza Dhillon, Gurbinder Onwumere, Juliana Prins, Anne-Marye Schepman, Karen Collier, Tracy White, Thomas P. Patel, Anita Gaughran, Fiona Shergill, Sukhwinder S. |
author_facet | Sarkar, S. Neil Tracy, Derek K. Fernandez, Maria-Jesus Mateos Nalesnik, Natasza Dhillon, Gurbinder Onwumere, Juliana Prins, Anne-Marye Schepman, Karen Collier, Tracy White, Thomas P. Patel, Anita Gaughran, Fiona Shergill, Sukhwinder S. |
author_sort | Sarkar, S. Neil |
collection | PubMed |
description | Aims and method In up to a quarter of patients, schizophrenia is resistant to standard treatments. We undertook a naturalistic study of 153 patients treated in the tertiary referral in-patient unit of the National Psychosis Service based at the Maudsley Hospital in London. A retrospective analysis of symptoms on admission and discharge was undertaken using the OPCRIT tool, along with preliminary economic modelling of potential costs related to changes in accommodation. Results In-patient treatment demonstrated statistically significant improvements in all symptom categories in patients already identified as having schizophrenia refractory to standard secondary care. The preliminary cost analysis showed net savings to referring authorities due to changes from pre- to post-discharge accommodation. Clinical implications Despite the enormous clinical, personal and societal burden of refractory psychotic illnesses, there is insufficient information on the outcomes of specialised tertiary-level care. Our pilot data support its utility in all domains measured. |
format | Online Article Text |
id | pubmed-4115394 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Royal College of Psychiatrists |
record_format | MEDLINE/PubMed |
spelling | pubmed-41153942014-08-21 Unheard voices: outcomes of tertiary care for treatment-refractory psychosis Sarkar, S. Neil Tracy, Derek K. Fernandez, Maria-Jesus Mateos Nalesnik, Natasza Dhillon, Gurbinder Onwumere, Juliana Prins, Anne-Marye Schepman, Karen Collier, Tracy White, Thomas P. Patel, Anita Gaughran, Fiona Shergill, Sukhwinder S. Psychiatr Bull (2014) Original Papers Aims and method In up to a quarter of patients, schizophrenia is resistant to standard treatments. We undertook a naturalistic study of 153 patients treated in the tertiary referral in-patient unit of the National Psychosis Service based at the Maudsley Hospital in London. A retrospective analysis of symptoms on admission and discharge was undertaken using the OPCRIT tool, along with preliminary economic modelling of potential costs related to changes in accommodation. Results In-patient treatment demonstrated statistically significant improvements in all symptom categories in patients already identified as having schizophrenia refractory to standard secondary care. The preliminary cost analysis showed net savings to referring authorities due to changes from pre- to post-discharge accommodation. Clinical implications Despite the enormous clinical, personal and societal burden of refractory psychotic illnesses, there is insufficient information on the outcomes of specialised tertiary-level care. Our pilot data support its utility in all domains measured. Royal College of Psychiatrists 2014-04 /pmc/articles/PMC4115394/ /pubmed/25237502 http://dx.doi.org/10.1192/pb.bp.112.042598 Text en © 2014 The Royal College of Psychiatrists http://creativecommons.org/licenses/by/3.0/ This is an open-access article published by the Royal College of Psychiatrists and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Papers Sarkar, S. Neil Tracy, Derek K. Fernandez, Maria-Jesus Mateos Nalesnik, Natasza Dhillon, Gurbinder Onwumere, Juliana Prins, Anne-Marye Schepman, Karen Collier, Tracy White, Thomas P. Patel, Anita Gaughran, Fiona Shergill, Sukhwinder S. Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title | Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title_full | Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title_fullStr | Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title_full_unstemmed | Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title_short | Unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
title_sort | unheard voices: outcomes of tertiary care for treatment-refractory psychosis |
topic | Original Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115394/ https://www.ncbi.nlm.nih.gov/pubmed/25237502 http://dx.doi.org/10.1192/pb.bp.112.042598 |
work_keys_str_mv | AT sarkarsneil unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT tracyderekk unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT fernandezmariajesusmateos unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT nalesniknatasza unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT dhillongurbinder unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT onwumerejuliana unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT prinsannemarye unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT schepmankaren unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT colliertracy unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT whitethomasp unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT patelanita unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT gaughranfiona unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis AT shergillsukhwinders unheardvoicesoutcomesoftertiarycarefortreatmentrefractorypsychosis |