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Frontiers in therapeutic development of allopregnanolone for Alzheimer’s disease and other neurological disorders

Allopregnanolone (Allo), a neurosteroid, has emerged as a promising promoter of endogenous regeneration in brain. In a mouse model of Alzheimer’s disease, Allo induced neurogenesis, oligodendrogenesis, white matter generation and cholesterol homeostasis while simultaneously reducing β-amyloid and ne...

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Detalles Bibliográficos
Autores principales:	Irwin, Ronald W., Solinsky, Christine M., Brinton, Roberta Diaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115668/ https://www.ncbi.nlm.nih.gov/pubmed/25126056 http://dx.doi.org/10.3389/fncel.2014.00203

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