Structured Cyclic Peptides That Bind the EH Domain of EHD1

[Image: see text] EHD1 mediates long-loop recycling of many receptors by forming signaling complexes using its EH domain. We report the design and optimization of cyclic peptides as ligands for the EH domain of EHD1. We demonstrate that the improved affinity from cyclization allows fluorescence-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamens, Alissa J., Eisert, Robyn J., Corlin, Tiffany, Baleja, James D., Kritzer, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116148/
https://www.ncbi.nlm.nih.gov/pubmed/25014215
http://dx.doi.org/10.1021/bi500744q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116148/
https://www.ncbi.nlm.nih.gov/pubmed/25014215
http://dx.doi.org/10.1021/bi500744q

Ejemplares similares