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Structured Cyclic Peptides That Bind the EH Domain of EHD1
[Image: see text] EHD1 mediates long-loop recycling of many receptors by forming signaling complexes using its EH domain. We report the design and optimization of cyclic peptides as ligands for the EH domain of EHD1. We demonstrate that the improved affinity from cyclization allows fluorescence-base...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116148/ https://www.ncbi.nlm.nih.gov/pubmed/25014215 http://dx.doi.org/10.1021/bi500744q |