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Extracellular HCV-Core Protein Induces an Immature Regulatory Phenotype in NK Cells: Implications for Outcome of Acute Infection

BACKGROUND: Hepatitis C viral (HCV) proteins, including core, demonstrate immuno-modulatory properties; however, the effect of extracellular core on natural killer (NK) cells has not previously been investigated. AIMS: To characterise NKs in acute HCV infection over time, and, to examine the effect...

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Detalles Bibliográficos
Autores principales: Golden-Mason, Lucy, Hahn, Young S., Strong, Michael, Cheng, Linling, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116173/
https://www.ncbi.nlm.nih.gov/pubmed/25076408
http://dx.doi.org/10.1371/journal.pone.0103219