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MDSCs Mediate Angiogenesis and Predispose Canine Mammary Tumor Cells for Metastasis via IL-28/IL-28RA (IFN-λ) Signaling

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) function in immunosuppression and tumor development by induction of angiogenesis in a STAT3-dependent manner. Knowledge of MDSC biology is mainly limited to mice studies, and more clinical investigations using spontaneous tumor models are required...

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Detalles Bibliográficos
Autores principales:	Mucha, Joanna, Majchrzak, Kinga, Taciak, Bartłomiej, Hellmén, Eva, Król, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116234/ https://www.ncbi.nlm.nih.gov/pubmed/25075523 http://dx.doi.org/10.1371/journal.pone.0103249

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