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Kinetochore–microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E
Centromere protein E (CENP-E) is a highly elongated kinesin that transports pole-proximal chromosomes during congression in prometaphase. During metaphase, it facilitates kinetochore–microtubule end-on attachment required to achieve and maintain chromosome alignment. In vitro CENP-E can walk process...
Autores principales: | Vitre, Benjamin, Gudimchuk, Nikita, Borda, Ranier, Kim, Yumi, Heuser, John E., Cleveland, Don W., Grishchuk, Ekaterina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116301/ https://www.ncbi.nlm.nih.gov/pubmed/24920822 http://dx.doi.org/10.1091/mbc.E14-01-0698 |
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