Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis

BACKGROUND: The classical paradigm of liver injury asserts that hepatic stellate cells (HSC) produce, remodel and turnover the abnormal extracellular matrix (ECM) of fibrosis via matrix metalloproteinases (MMPs). In extrahepatic tissues MMP production is regulated by a number of mechanisms including...

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Detalles Bibliográficos
Autores principales: Calabro, Sarah R., Maczurek, Annette E., Morgan, Alison J., Tu, Thomas, Wen, Victoria W., Yee, Christine, Mridha, Auvro, Lee, Maggie, d'Avigdor, William, Locarnini, Stephen A., McCaughan, Geoffrey W., Warner, Fiona J., McLennan, Susan V., Shackel, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116334/
https://www.ncbi.nlm.nih.gov/pubmed/25076423
http://dx.doi.org/10.1371/journal.pone.0090571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116334/
https://www.ncbi.nlm.nih.gov/pubmed/25076423
http://dx.doi.org/10.1371/journal.pone.0090571

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