BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease

Erdheim-Chester disease (ECD) is a rare histiocytosis with a high prevalence of BRAF V600E mutation (>50% of patients). Patients with BRAF-mutant ECD can respond to BRAF inhibitors. Unfortunately, the lack of adequate archival tissue often precludes BRAF testing. We hypothesized that cell-free DN...

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Detalles Bibliográficos
Autores principales: Janku, Filip, Vibat, Cecile Rose T., Kosco, Karena, Holley, Veronica R., Cabrilo, Goran, Meric-Bernstam, Funda, Stepanek, Vanda M., Lin, Patrick P., Leppin, Lorieta, Hassaine, Latifa, Poole, Jason C., Kurzrock, Razelle, Erlander, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116506/
https://www.ncbi.nlm.nih.gov/pubmed/25003820

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