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Proliferation, differentiation and amyloid-β production in neural progenitor cells isolated from TgCRND8 mice
The amyloid precursor protein (APP) and amyloid-β (Aβ) peptide play central roles in the pathology and etiology of Alzheimer’s disease. Amyloid-induced impairments in neurogenesis have been investigated in several transgenic mouse models but the mechanism of action remains to be conclusively demonst...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116598/ https://www.ncbi.nlm.nih.gov/pubmed/24361736 http://dx.doi.org/10.1016/j.neuroscience.2013.12.021 |