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The multifunctional and multi-system influence of Ghrelin in the treatment of diabetic and spinal cord injury induced Neuropathy

Ghrelin (Gh), a small peptide, which was originally discovered as a gastrointestinal (GI) tropic hormone, has shown to have a presence and function within multiple tissue systems. Recently, Gh has shown to exhibit anti-inflammatory and regenerative abilities in response to both chemical and mechanic...

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Detalles Bibliográficos
Autores principales: Fields, DP, Miranpuri, SS, Miranpuri, GS, Resnick, DK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116944/
https://www.ncbi.nlm.nih.gov/pubmed/25205937
http://dx.doi.org/10.5214/ans.0972.7531.1118309
Descripción
Sumario:Ghrelin (Gh), a small peptide, which was originally discovered as a gastrointestinal (GI) tropic hormone, has shown to have a presence and function within multiple tissue systems. Recently, Gh has shown to exhibit anti-inflammatory and regenerative abilities in response to both chemical and mechanical stressors within neural tissues. By continuing to elucidate the potential applications of Gh on pathological neural states, the viability of this peptide hormone for therapeutic uses can be explored for future clinical application.