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Vasospasm: A friend or foe - initial experience

BACKGROUND: The optimal time to operate on an intracranial aneurysm eludes a satisfactory answer. While most surgeons would agree to operate early in young and neurologically intact patients, the ideal timing in older and neurologically impaired patients is debatable. In India, the majority of cente...

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Autores principales: Mukherjee, KK, Jain, VK, Chhabra, DK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117046/
https://www.ncbi.nlm.nih.gov/pubmed/25205970
http://dx.doi.org/10.5214/ans.0972.7531.12190206
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author Mukherjee, KK
Jain, VK
Chhabra, DK
author_facet Mukherjee, KK
Jain, VK
Chhabra, DK
author_sort Mukherjee, KK
collection PubMed
description BACKGROUND: The optimal time to operate on an intracranial aneurysm eludes a satisfactory answer. While most surgeons would agree to operate early in young and neurologically intact patients, the ideal timing in older and neurologically impaired patients is debatable. In India, the majority of centers operate on patients in Hunt and Hess grades I-III, but is circumspect about grades IV and V. PURPOSE: The following study was carried out to check the effect of vasospasm on mortality rates and time of surgery being performed on the patient after having the same in patients coming under criteria of Hunt and Hess grades IV and V METHODS: We undertook a prospective evaluation of 171 consecutive patients of aneurysms operated during the last 9 years irrespective of their age, neurological grade, and time of presentation or vasospasm in an attempt to resolve this issue. The influence of vasospasm on each neurological grade was examined. RESULTS: It appears that concomitant presence of vasospasm in grade III, IV and V patients indicates a possible “reversible” cause of the poor neurological status, while its absence may indicate an irreversible or more extensive primary insult. CONCLUSION: The presence of vasospasm in poor grade patients appears to be a better prognostic indicator.
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spelling pubmed-41170462014-09-09 Vasospasm: A friend or foe - initial experience Mukherjee, KK Jain, VK Chhabra, DK Ann Neurosci Research Article BACKGROUND: The optimal time to operate on an intracranial aneurysm eludes a satisfactory answer. While most surgeons would agree to operate early in young and neurologically intact patients, the ideal timing in older and neurologically impaired patients is debatable. In India, the majority of centers operate on patients in Hunt and Hess grades I-III, but is circumspect about grades IV and V. PURPOSE: The following study was carried out to check the effect of vasospasm on mortality rates and time of surgery being performed on the patient after having the same in patients coming under criteria of Hunt and Hess grades IV and V METHODS: We undertook a prospective evaluation of 171 consecutive patients of aneurysms operated during the last 9 years irrespective of their age, neurological grade, and time of presentation or vasospasm in an attempt to resolve this issue. The influence of vasospasm on each neurological grade was examined. RESULTS: It appears that concomitant presence of vasospasm in grade III, IV and V patients indicates a possible “reversible” cause of the poor neurological status, while its absence may indicate an irreversible or more extensive primary insult. CONCLUSION: The presence of vasospasm in poor grade patients appears to be a better prognostic indicator. Indian Academy of Neurosciences 2012-04 /pmc/articles/PMC4117046/ /pubmed/25205970 http://dx.doi.org/10.5214/ans.0972.7531.12190206 Text en Copyright © 2012, Annals of Neurosciences
spellingShingle Research Article
Mukherjee, KK
Jain, VK
Chhabra, DK
Vasospasm: A friend or foe - initial experience
title Vasospasm: A friend or foe - initial experience
title_full Vasospasm: A friend or foe - initial experience
title_fullStr Vasospasm: A friend or foe - initial experience
title_full_unstemmed Vasospasm: A friend or foe - initial experience
title_short Vasospasm: A friend or foe - initial experience
title_sort vasospasm: a friend or foe - initial experience
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117046/
https://www.ncbi.nlm.nih.gov/pubmed/25205970
http://dx.doi.org/10.5214/ans.0972.7531.12190206
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