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Development of time-resolved fluorescent based [EU]-GTP binding assay for selection of human Histamine 3 receptor antagonists/inverse agonist: a potential target for Alzheimer’s treatment

BACKGROUND: The histamine H3 receptor is an attractive G protein–coupled receptor drug target that regulates neurotransmission in the central nervous system and plays a crucial role in cognitive and homeostatic functions. This receptor exhibits molecular, pharmacological, and functional heterogeneit...

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Detalles Bibliográficos
Autores principales:	Singh, Jitendra K., Maniyar, Reema C., Shirsath, Vikas S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Indian Academy of Neurosciences 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117047/ https://www.ncbi.nlm.nih.gov/pubmed/25205969 http://dx.doi.org/10.5214/ans.0972.7531.12190205

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