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Correlated Inter-Domain Motions in Adenylate Kinase

Correlated inter-domain motions in proteins can mediate fundamental biochemical processes such as signal transduction and allostery. Here we characterize at structural level the inter-domain coupling in a multidomain enzyme, Adenylate Kinase (AK), using computational methods that exploit the shape i...

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Detalles Bibliográficos
Autores principales:	Esteban-Martín, Santiago, Fenwick, Robert Bryn, Ådén, Jörgen, Cossins, Benjamin, Bertoncini, Carlos W., Guallar, Victor, Wolf-Watz, Magnus, Salvatella, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117416/ https://www.ncbi.nlm.nih.gov/pubmed/25078441 http://dx.doi.org/10.1371/journal.pcbi.1003721

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